Current Study: D 6

Purpose
• To determine how the investigational drug is broken down and removed from the body in volunteers with liver impairment when compared to volunteers with normal liver function
• Information regarding safety and side effects that may occur will also be collected
• This study is for research purposes only and is not intended to treat your liver disease

Method of Administration
Single oral dose of study medication

To qualify
• 18 to 75 years old
• Diagnosed with liver disease or liver damage
• May have cirrhosis due to Hepatitis B or C, fatty liver disease, including NASH, or history of alcohol-related liver disease
• May be taking medicines such as spironolactone, furosemide, lactulose, or Xifaxan®
• May have fluid in your abdomen or previous encephalopathy (brain condition that causes irritability, sleepiness, or trouble sleeping)

Length/Duration
• 12 consecutive days and 11 nights in our research facility

Location
5055 South Orange Avenue, Orlando, FL 32809

Qualified participants will receive study medication, study related physical exams and laboratory tests
Qualified study participants will be compensated up to $3,050 for time and travel

Whom to Contact
Recruitment Department: 407-240-7876