Current Study: I5

Study: I5

Investigator: Thomas Marbury
Research Study: Liver Study

• The overall purpose for this study is to find out if the study drug is absorbed or
eliminated differently in people with normal liver function compared to people with
impaired liver function. Another purpose is to assess the safety and tolerability of the
study drug in people with healthy and impaired liver function.
• This study is for research purposes only and is not intended to treat your liver

Method of Administration: Single oral dose

Investigator: Thomas Marbury, MD

To qualify:

• 18 years to 70 years old
• Must have decreased liver function or disease such as fatty liver disease (NASH),
Hepatitis C, past history of alcohol related liver disease or cirrhosis
• Volunteers may be taking medicines such as spironolactone (Aldactone®),
furosemide (Lasix®), lactulose, or rifaximin (Xifaxan®)
• May also have ascites (fluid in your abdomen) or encephalopathy (brain condition
that causes irritability or trouble sleeping)
• Other eligibility requirements apply

• 1 eligibility screening visit
• 11 days and 10 nights in our research facility
• 1 follow-up visit

Location: 5055 South Orange Avenue, Orlando, FL 32809

Qualified participants will receive study medication, study related physical exams and laboratory tests

Compensation Qualified participants will be compensated up to $3,875 for time and travel

Whom to Contact Recruitment Department: 407-240-7876

Orlando Clinical Research Center
5055 South Orange Avenue
Orlando, FL 32809

Recruiting Number: 407.240.7878

Apply now for Study: I5