Current Study: T8

Purpose:

• To determine how the investigational drug is broken down and removed from the body in volunteers with various degrees of liver impairment when compared to volunteers with normal liver function
• Information regarding safety and side effects that may occur will also be collected
• This study is for research purposes only and is not intended to treat your liver disease

Method of Administration: Single oral dose of study medication

To qualify:

• 18 to 79 years old
• Must have decreased liver function or disease such as fatty liver disease (NASH), Hepatitis C (if treated successfully), past history of alcohol related liver disease or cirrhosis
• Volunteers may be taking medicines such as spironolactone, Lasix®, lactulose, Aldactone®, or rifaximin
• May also have fluid in your abdomen or encephalopathy (brain condition that causes irritability or trouble sleeping)

Length/Duration:
• 11 days and 10 nights in our research facility
• 1 follow-up phone call

Location: 5055 South Orange Avenue, Orlando, FL 32809

Qualified participants will receive study medication, study related physical exams and laboratory tests

Compensation: Qualified study participants will be compensated up to $2,850 for time and travel

Whom to Contact: Recruitment Department: 407-240-7876