Current Study: E3

Purpose:

• To determine how an investigational drug is broken down and removed from the body in volunteers with liver impairment relative to volunteers with normal liver function
• Information regarding side effects that may occur will also be collected
• This study is for research purposes only and is not intended to treat your liver disease

Method of Administration: Single oral dose of study drug

Investigator: Thomas Marbury, MD

To qualify:
• 18 to 85 years old
• Must have liver disease such as fatty liver disease (NASH), Hepatitis C, past history of alcohol related liver disease or cirrhosis (liver scarring)
• Volunteers may be taking medicines such as spironolactone (Aldactone®), furosemide (Lasix®), lactulose, or rifaximin (Xifaxan®)
• May also have ascites (fluid in your abdomen) or encephalopathy (brain condition that causes irritability or trouble sleeping)

Study details:
• 5 days and 4 nights in our research facility
• 4 follow-up visits

Qualified participants will receive study medication, study related physical exams and laboratory tests

Location: 5055 South Orange Avenue, Orlando, FL 32809

Compensation: Qualified participants will be compensated up to $3,175 for time and travel

Whom to Contact: Recruitment Department: 407-240-7876