Orlando Clinical Research Center (OCRC) is an independent Phase I-IV custom built 35,000 sq. ft. research site specifically designed for Phase 1 trials. The facility includes 90 in-house volunteer beds situated between 26 separate dorm-style rooms, dual lead digital telemetry, an upgraded security system with card key access and digitally recorded cameras, as well as a special treatment/observation area with 12 hospital beds (6 of which are plumbed for onsite hemodialysis).

OCRC recognizes the importance of timely start-up and thorough documentation processing from initial contact through completion. We offer a full spectrum of services designed to ensure the smooth operation and success of your trial. From study initiation to closeout, your project has a dedicated team committed to excellence… committed to you.

OCRC is conveniently located in the medical district of central Florida with easy access to the Orlando International Airport, hotel accommodations, and area attractions.


Our streamlined and thorough planning, coordination and monitoring process ensures both efficiency and exacting quality. At OCRC our qualifications include:

Full time, On-Site Physician Investigator and Certified Clinical Research Coordinators
Pre-study & Initiation visits
Protocol development & review
Medical management
Preparation of source documents
Comprehensive subject recruitment & enrollment tracking
CRF completion, drug accountability, AE review and reporting
Dedicated regulatory team
Informed consent preparation/review
Regulatory document collection and processing
Use of central Institutional Review Boards

Volunteer Recruitment

Centered in the nation’s most popular tourist attraction destination OCRC has accrued a broad participant base that is continually updated and replenished through referrals from advertisements, private practices, dialysis centers, universities, and retirement communities.

Our dedicated recruitment staff maintains an ever-expanding and detailed database that allows us to access suitable volunteers based on important demographic input that encompasses all major groups for volunteer populations.

We also have excellent relationships with the local newspaper, radio and television stations to facilitate and maintain affordable and effective advertising for studies as necessary.

Data Management Capabilities

Conventional CRF entry
Remote data entry
Web based data capture
Electronic data transfer – (ECG, rigiscan, glucose monitors, ABPM, Holter)

Our Facility Includes:
The Orlando Clinical Research Center (OCRC) remains on the frontier of clinical research, an independent, Phase I-IV, custom-built 35,000 sq.ft. research site specifically designed for Phase I trials. The facility includes:

– 90 beds for dormitory style patient confinement with separate accommodations for men and women
– Separate Large Intensive treatment/observation area for specialty service with 12 hospital beds (6 are plumbed for dialysis)
– Hemodialysis done onsite in our facility for the ultimate in flexibility of hemodialysis PK studies
– Recreational amenities include: Cable TV in all dorm rooms with VCR and DVD players, Quiet Room with cable modem internet access, WiFi access throughout
– 24-hour medical supervision
– 12 Examination rooms
– Within 3 miles of Level 1 Trauma Center
– Alarm System Security with closed circuit TV and card key access
– Specified private client monitoring areas with phone lines and cable modem access
– Certified sample processing laboratory
– Special laboratory processing techniques and equipment to include a class II Bio-safety cabinet, Laboratory freezers (-70°C and -20°C)
– Refrigerated Centrifuges
– Computerized ECG machines
– Secured storage for a drug supplies and documents
– Dynamaps with printers
– Spirometry
– IV infusion pumps
– Dual Lead Digital Telemetry
– Holter Monitoring

Phase 1

First time in Man Safety / Tolerance
Bioavailability / Bioequivalence
Pharmacokinetics / Pharmacodynamics
Dose Response
Food effect Studies
IV Infusion Studies
Drug Interactions
Metabolic Balance
Special Populations (Healthy, Renal, Hepatic, Diabetic, Post-Menopausal, Testosterone
Deficiency, Elderly, Obesity)

Phase II-IV

Prescription and over the counter (OTC) conversion
Post-marketing studies
Claims and labeling support
Dose ranging and definition
Clinical Efficacy and Safety
Therapeutic areas
Weight loss
Smoking cessation
Diabetes (Type I, Type II)
Lipid Studies


Sun Damage
Actinic Keratoses
Macular Degeneration
Herpes Simplex Virus
Genital Herpes
Cold Sores
Testosterone Deficiency
Erectile Dysfunction
Birth Control

Thomas C. Marbury, MD

Thomas C. Marbury, MD

Thomas C. Marbury, MD, is one of the pioneers in clinical research and has served as Principal Investigator in over 1,300 Clinical Trials since 1978. He has published extensively in scientific and clinical journals in the area of renal and hepatic pharmacokinetics. He is the founder and President of Orlando Clinical Research Center since 1990. As the President of Orlando Clinical Research Center, his main areas of research are Phase 1 clinical trials.

Dr. Marbury is a graduate of the University of Texas Medical School and is board certified in Internal Medicine and Nephrology. He did a Nephrology Fellowship at the University of Florida with Robert Cade, the inventor of Gatorade. At the encouragement and invitation of Dr Cade, he joined the full time Nephrology Faculty, directing a hypertension research lab, conducting clinical research trials, and became an Assistant Professor at the University of Florida. He was also the Head of Adult Dialysis Programs, and Chief of Nephrology at the Gainesville VA hospital. He moved to Orlando in 1981 to join a Private practice, Internal Medicine Specialists. He was Chief of Nephrology at Orlando Regional Medical Center for over 20 years and was a co-founder of several dialysis units in the Orlando area. He retired from private practice in 2000 to concentrate on his clinical research studies and devote his full time as President of Orlando Clinical Research Center.

Our Company Values – The eight keys that define our organization

We will strive to embody the eight values that are embedded right in our organization’s name, OCRC.

O: Outstanding & Open-Minded
• We will work to the best of our abilities to achieve high results.
• We know the products we send to our sponsors are a reflection of our organization and ourselves, so we will work diligently to ensure excellence.
• We will provide the best care to our subjects entrusted with our care.

C: Collaborative & Communicative
• We believe in teamwork and collaboration to meet joint goals.
• We understand communication is key both within our organization and our external partners.
• We will come together to identify problems and produce solutions that are good for the organization and all parties involved.

R: Respectful & Reliable
• We will treat those we encounter with the highest regard, including staff, subjects and external partners.
• We will honor the time of other people and be mindful of our teammate’s schedules and workloads.
• We will interact with each other in professional ways including what we say and do.
• We will demonstrate consistency in performance, effectiveness, and quality of work.

C: Courageous & Committed
• We will have the courage to do what is right, with everything we do.
• We are always giving of our time and best effort for an assigned project.
• We will advocate for those within our organization and on behalf of our subjects.

Downtown Area

The Delaney Hotel
315 S. Orange Ave., Orlando, FL 32806
Phone: (407) 606-7130 | Email: info@staydh.com

Grand Bohemian
(approx. 3 miles North of OCRC)
325 S. Orange Ave.,
Orlando, FL 32801
(407) 313-9000

Hampton Inn & Suites Downtown
(approx. 3 miles North of OCRC)
43 Columbia St
Orlando, FL 32806
(407) 270-6460

Courtyard by Marriott Orlando Downtown
(approx. 3.5 miles North of OCRC)
730 N. Magnolia Ave.,
Orlando, FL 32803
(407) 996-1000
www.marriott.com/hotels/travel/ mcoma-courtyard-orlando-downtown

Residence Inn by Marriott Orlando Downtown
(approx. 5 miles North of OCRC)
680 N. Orange Ave.,
Orlando, FL 32801
(407) 482-1500

Near Orlando Shopping & Attractions

The Florida Hotel and Conference Center at the Florida Mall (approx. 4 miles South of OCRC)
1500 Sand Lake Rd., Orlando, FL 32809
(407) 859-1500

Portofino Bay Hotel (at Universal Studios City Walk)
5601 Universal Blvd., Orlando, FL 32819
(866) 629-1916

The Peabody Orlando
9801 International Dr.,
Orlando, FL 32819
(800) 732-2639

Omni Rosen Hotel
9840 International Dr.,
Orlando, FL 32819
(407) 354-9840

Rosen Centre Home

Near Orlando International Airport

The Orlando Airport Marriott
7499 Augusta National Dr.,
Orlando, Florida 32822
(800) 766-6752

Hampton Inn & Suites Orlando International Airport
(approx. 5 miles South of OCRC near Airport)
5460 Gateway Village Circle
Orlando, FL 32812
(407) 857-2830

Hyatt Orlando Airport
(approx. 5 miles South of OCRC)
Terminal Area of Airport
(407) 825-1234

Orlando Clinical Research Center
5055 South Orange Avenue
Orlando, FL 32809

Phone: 407-240-7878
Fax: 407-240-9846


From Orlando International
Airport Take AIRPORT BLVD Southeast
Stay STRAIGHT to go onto AIRPORT BLVD – 1.0 miles
Take the SR-528 TOLL W exit, EXIT 1B, toward INTERNATIONAL DR/I-4/FLORIDA’S TURNPIKE – 0.3 miles
Merge onto FL-528 TOLL W – 2.3 miles
Take the MCCOY RD/SR-482 exit, EXIT 8, toward SAND LAKE RD – 0.2 miles
Stay STRAIGHT to go onto MCCOY RD/FL-482 W – 1.0 miles
Keep RIGHT at the fork to continue on MCCOY RD/FL-482 W – 8.0 miles
Turn RIGHT onto ORANGE AVE S/S ORANGE AVE/FL-527 – 2.7 miles

From Florida’s West Coast
Take I-4 East
Merge onto US-17 92/S ORANGE BLOSSOM TRL/US-441 S via exit number 80A – 1.1 miles
Turn LEFT onto W HOLDEN AVE – 1.3 miles
Turn RIGHT onto S ORANGE AVE/FL-527 – 0.4 miles

From Florida’s East Coast
Take I–4 West
Take the MICHIGAN ST. exit- exit number 81A – 0.1 miles
Turn SHARP LEFT onto W MICHIGAN ST – 0.9 miles
Turn RIGHT onto S ORANGE AVE/FL-527 – 1.7 miles