Current Study: G 6

Purpose:

• To determine how the investigational drug is absorbed, broken down, and removed from the body in volunteers with various degrees of kidney impairment when compared to volunteers with a normal level of kidney function.
• Information regarding safety and side effects that may occur will also be collected.
• This study is for research purposes only and is not intended to treat your kidney disease.

Method of Administration: Single oral dose of study drug

Investigator: Thomas Marbury, MD

To qualify:

• 18 to 79 years old
• Must have kidney impairment or disease, meaning your kidneys do not function at a normal level, but not require dialysis
• May be seeing a nephrologist (a doctor that specializes in kidneys) and may be taking medicine such as:

• Procrit® or Aranesp® for low blood count
or
• PhosLo® or Renagel® for high blood phosphorus

• Additional qualifying criteria exists

Length/Duration:
• 12 day, 11 night stay in our research dormitory
• 1 follow-up phone call

Location: 5055 South Orange Avenue, Orlando, FL 32809

Qualified participants will receive study drug, study related physical exams and laboratory tests

Compensation:
Qualified participants will receive compensation up to $4,150 for study-related time and travel upon study completion

Whom to Contact Recruitment Department: 407-240-7876