Current Study: G2

Purpose:
• To determine how the investigational drug is broken down and removed from the body in volunteers with a severe degree of liver impairment when compared to volunteers with normal liver function
• Information regarding safety and side effects that may occur will also be collected
• This study is for research purposes only and is not intended to treat your liver disease

Method of Administration:
Subcutaneous injection (just beneath the skin) of study medication once daily for 6 days

Investigator: Thomas Marbury, MD

To qualify:
• 18 years to 79 years old
• Must have decreased liver function or disease such as fatty liver disease (NASH), Hepatitis C (if treated successfully), or past history of alcohol related liver disease
• Volunteers may be taking medicines such as spironolactone, lactulose, or rifaximin
• May also have fluid in your abdomen or cirrhosis

Length/Duration:
• 9 days and 8 nights in our research facility
• 1 follow-up phone call

Location: 5055 South Orange Avenue, Orlando, FL 32809

Compensation: Qualified participants will be compensated up to $3,100 for study related time and travel upon completion

Qualified participants will receive study medication, study related physical exams and laboratory tests

Whom to Contact: Recruitment Department: 407-240-7876