Current Study: S 3

Purpose:
• The overall purpose of this study is to find out if the study drug is absorbed or eliminated differently in individuals with normal liver function compared to individuals with impaired liver function. Another purpose is to assess the safety and tolerability of the drug in people with healthy to impaired liver function.
• This study is for research purposes only and is not intended to treat your liver disease

Method of Administration:  Single oral dose of study drug

To qualify:
• 18 to 80 years old
• Must have decreased liver function or disease such as fatty liver disease (NASH), history of Hepatitis C, past history of alcohol related liver disease or cirrhosis
• Volunteers may be taking medicines such as spironolactone (Aldactone®), furosemide (Lasix®), lactulose, or rifaximin (Xifaxan®)
• May also have ascites (fluid in your abdomen)

Length/Duration:
• 9 days and 8 nights in our research facility
• 1 follow-up phone call

Location:
5055 South Orange Avenue, Orlando, FL 32809

Compensation:
Qualified participants will receive study medication, study related physical exams and laboratory tests
Qualified participants will be compensated up to $4,300 for time and travel

Whom to Contact:
Recruitment Department: 407-240-7876